Cali Fires

Maybe I'm a closet pyro, but I am fascinated by wildfires and wilderness firefighting of late. Check out this awesome google mashup by the San Diego Union-Trib.

Alcohol as a therapeutic?

From Australia (where else?) comes this gem of a story about alcohol being used therapeutically:

DOCTORS used a case of vodka to help save an Italian tourist being treated for poisoning in a Queensland hospital. And hospital authorities later proved very understanding about the booze bill. The 24-year-old man was brought to Mackay Base Hospital, in north Queensland, two months ago after he had ingested a large amount of the poisonous substance ethylene glycol, found in antifreeze, which can cause renal failure and is often fatal.

Well I got curious, of course, as to how exactly it was possible for alcohol to be GOOD for you (asides from red wine, but then its not the booze in red wine that's helping you, but some of the other stuff). I also got curious, however, because this story directly relates to the Chinese Poison Toothpaste Fiasco that has been leading headlines this year (you may recall, ethylene glycol is similar to glycerine and was substituted in toothpastes made in China).

Luckily, the beauty of the modern 'radiated library' known as the internet has merged with the 1980s/90s 'evidence-based medicine' movement to let average Joes like me access lots of free medical information. Here, you can find "Methanol and ethylene glycol poisoning: a case study and review of the literature" which neatly summarizes (in fairly penetratable medspeak) exactly what happens with ethylene glycol poisoning.


Essentially, ethylene glycol and alcohol go through the same metabolic pathways in the body, and thus are broken down by the same compounds. Ethylene glycol itself is not poisonous, it is its after-molecules that cause trouble. Oxalate acid in particular has a tendancy to build up in certain bodily tissues, especially the kidneys. This 'oxalate crystal deposition' is a primary mechanism of ethylene glycol's toxicity, and leads to kidney failure (and potentially death). This is ethylene glycol's metabolic pathway:

Treating ethylene glycol poisoning is really easy, you first have to block the molecule's metabolic pathways, to prevent further harm. This is usually accomplished with IV ethanol (alcohol) or fomepizole, and seeks to block the action of ADH in metabolizing the compound. Fomepizole simply inhibits the ability of ADH to do its work, while ethanol 'competes' with ethylene glycol for ADH floating around in your system. It turns out that booze is 100 TIMES more able to soak up ADH than ethylene glycol, so putting just a little bit of alcohol into your system quickly takes up all the available ADH, simply preventing ethylene glycol from breaking down while you are drunk. In the meantime, while ADH is being blocked, ethylene glycol is simply floating around, not dangerous, but not going away. Simple hemodialysis (filtering of the blood through an external machine) can accomplish the task of scrubbing your blood of the ethylene glycol.

This is why the docs gave the guy 3 drinks an hour for 3 days, because they essentially needed to keep him long-term buzzed , to prevent his kidneys from failing, while they scrubbed his blood. I guess he took so much, that it took them a while. HAH.

Also check out wikipedia.

More cool architecture

I've been seeing some pretty cool buildings lately, in a sort of 21st century modernism based on glass, steel, aluminum and totally unconventional vertical aesthetics. It's funny how much our impression of buildings is rooted in our deep reliance on the functionality of buildings, as solid structures whose stability protects us from the element. It seems that we therefore prize solid, secure aesthetics, namely the importance of 90 degree angles. Even the Bilbao Guggenheim ascribes to this innate need for secure stability. Despite its titanium sides and smoothly fluid lines, it is fundamentally squatly anchored in the ground.

Newer 21st century architecturs even seem to challenges this, I have been noticing. This new architecture seems to revel in illusions of instability through leaning, slumping, and surging at angles neither paralell, nor perpindicular to the horizon. Three examples:

Stata Center, MIT

The new crystal addition to the Royal Ontario Museum:

And my personal favorite, the new Central Chinese Television Tower (CCTV), being built, in Beijing:

Slumping

This is one of my favorite pieces of architecture that I've seen in a while.

Feels to me like the silver parts of the building are slumping up against the brick, like an idle laborer smoking a cigarette, or someone waiting on the streetcorner to meet a friend. Nice. From a nice Slate slideshow.

On the nature of art

How pompous a title is that? Perhaps I should delete this post before I write it. Anyway, good piece from Slate, my favorite online mag, about Jack Kerouac's On the Road Again. While I haven't read the book (much to my friend MQ's disgust), my general point is simply not about the book, but on the general thesis of the piece:

Which is why it's no wonder that On the Road, a book that we've termed an
American Sacrament, is almost as widely and passionately viewed as an American
Sham. This started around the time the novel was published, when Truman Capote
insulted Kerouac's prose as "typing not writing," and has continued until this
afternoon, as shown by the profusion of readers' spitballs aimed at our rather
reverent discussion here. (One of these can be found under the heading
"Kerouac's 50 years of Crap," and it's not even the unkindest.) Would the novel
have been better as a memoir, you asked in your last note. Don't know. What I do
know is that there are countless detractors out there who don't regard it as a
novel at all but as a load of pretentious mental slobber. It might or might not
reflect true-life events, but it's still, to the skeptics, a bucket of foamy
word-slop that, for some devious or self-seeking reason (canny marketing by its
publishers? The doltishness of our nation's youth? The narcissism of baby
boomers who see the novel as their own creation myth?) has been borne along like
a chalice all these years and deserves, at long last, to be tossed back into the
gutter where its shiftless characters so often slept.

This discussion to me, while seemingly tangential, is actually the very heart of what the book was about. Or any book, movie, painting, poem etc. is about. It is not what the book says, or how it says it, or the detail of its prose, or the power of its central theme, or the detail of
its characters, or the passion of its writing. While all of these are independently worthwile, interesting, and engaging, to me the essence of art is simply that it got us going in the first place. I reject the notion that there is an objective 'good' or 'bad' about human art, yet I relish the argument about whether it is good or bad!

Even the haters in the above paragraph have emerged as better, more informed, more dynamic, more human after reading the book....even if they thought it was a huge piece of shit. People are thinking, and talking, and feeling, and debating about this book. They argue endlessly, and take positions, and think of new perspectives and new concepts. None of the actual opinions are material (at least to me), but it is the creation of those opinions that warms my heart, and makes me confident that the human race is in good hands. We'll be all right.

My ipod dilemma

So those of my paltry few readers who know me know that I am a born contrarian- socially, ideologically, politically, economically, but above all, technologically. In fact, I distinctly remember passionately arguing the merits of tapes over CDs in a soccer practice stretching circle when I was 10. I have thus resisted cellphones, Facebook and innumerable other important, major innovations since then. Each of these has been overcome in turn. It is a major, major flaw. I'm working on it.

Now comes the last one....I dont own an ipod. In fact, I dont even own an mp3 player of any kind. It's been on my to do list forever...buy ipod. Well, the announcement of the new iPod touch is obviously turning everything on its head.

I'm wondering....I love the touch, but the nano is also interesting. They've redesigned it and it now has video. On the other hand, the touch is the future! I cant decide. Size or coolness? Portability or wireless?

On a separate note, Apple cut the price of the iphone by $200!, which pissed everyone off who had already bought one. Check out the Consumerist:

Early Adopter Syndrome can strike anyone—our fancy N95 is less than six months old and has just been kicked to the curb by Nokia for a new version that works with US 3G—so we sympathize with all of you who just shelled out $600 for that great iPod/so-so phone combo from Apple. The Unofficial Apple Weblog offers the following five suggestions on how to fix your little $200 problem.

Apple however, has frankly done A+ PR damage control on this. When I first heard this, I thought big deal, I frankly didnt have a lot of sympathy for the early adopters. The blogosphere and internet went wild though, as seen above. To their credit, apple decided to contain the damage and are now offering $100 rebates to everyone who already bought one. Wow. Check out the letter one dude wrote to Steve Jobs from the Consumerist:

The business behind your idea is quite clear, and makes sense I admit. Introduce a product with a higher price and let those who will buy it at that price do so, and then decrease the price after you have saturated demand at the higher price. Despite the good business behind it, even as an owner of Apple stock I am still offended, and disappointed with your decision at the lack of integrity, and penny-pinching which this reflects on you and your company.

Decreasing the price of the 8 GB iPhone without offering some sort of refund or even Apple store credit to the faithful who rushed out to support your product and made it the sensation that it has become is a disservice to your followers; and leaves this fanboy for one not only feeling taken advantage of, but also at least a little less enchanted with you and your company.

I hope that you will take steps to make this right by your loyal followers who feel that they have been taken for fools.

Impressive argument. I have to say it also illustrates that the iphone sales are probably sluggish, largely due to apple's idiotic decision to only go with AT&T, buggy issues, and its lack of true revolutionary stuff. The ipod price only got cut today, after they introduced their own successor. The ipod touch, however, seems pretty awesome to me.

Now a real sign of the rosy future

From my buddy TF comes this amazing video:

Completely mind controlled!!!

To use the system, a person wears a lightweight sensor band around the neck. The band picks up the larynx nerve signals and transmits them wirelessly to a remote computer (don't worry about "mind wiretapping" -- the transmission is encrypted.) The remote computer uses NI LabVIEW and signal processing algorithms to interpret the nerve-impulse patterns and translate them into the right commands.

The system is not plug-and-play. It does require some training until its algorithms learn to "read your mind" (accuracy is above 70 percent). But at least it doesn't require Matrix-style brain interfaces or a tangle of EEG electrodes wrapped around your head

There are some links about it:

Spectrum Online

Company website: Ambient

This guy has his whole material life online

It's amazing! And its catalogued by colour, size, material, use, usage amount, location, cost, and ownership. From perusing his life, its obvious he's a photographer (asides from the fact he took thousands of pretty good pictures) because he has about 14 of these:

plus gadgety stuff like this:Anyway, I'm guessing that this is him and his partner:

But I could definitely be wrong.

Anyway, its a bizarre scene, but I like it, I think its amazingly cool. When I found it earlier this afternoon I was blown away...my friend ER was far less impressed. She was appalled. Why do I like it?

Mainly because it represents the unadulterated freedom of the internet.

Maybe also because I'm an unabashed contrarian. Many people would and will recoil in horror at the very concept of having the whole of their worldly possessions cataloged in intimate detail for everyone to peruse. I'm pretty sure I wouldn't do it, but that doesn't really hold me back from looking at the pictures in intimate detail. I mean, as I look at them, I try to puzzle out who this guy and his partner are, as human beings, but the more I try, the more I realize he's getting the last laugh.
Everyone is out there, right now, sifting through the material detritus of his life trying to understand him, or at least relate, or something. Their quest, and my quest, is ultimately futile. We can never even come close, with even this intimate a set of detailed miscellanea.

Pretty cool.

Slate answers another question I had before I even asked it

As usual, Slate is right on top of the news and has answered a critical question for me about current events. Why was everyone so worked up about the fires in Greece getting close to Olympia? Aren't they just stone? Not so, says Slate, apparently fire can reduce them to dust.